Edition 38, sent 2010-03-26 15:02:07
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Travel Medicine Alliance Update eNewsletter - health news & information for international travellers

Outbreak information and news in Travel Medicine Alliance eUpdate - read on-line from archives here
TRAVEL MEDICINE ALLIANCE UPDATE

Travel Medicine Alliance eUpdate - health news & information for international travellers

March 2010

1300 42 11 42

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In this issue:

Outbreak Information and News
Tick Borne Encephalitis (TBE) has been found on Zealand
Northern Hemisphere Flu
Germany - Hantavirus
Fiji - Cyclone Tomas
Turkey - Earthquake
Kenya, Rwanda, Uganda - Flooding
Sri Lanka - Dengue
Honduras - Dengue
Argentina - Dengue

Lhasa to Kathmandu via mountain bike

Lessons From A Dengue Epidemic In North Queensland

Interesting travel photo - fish catches the fisherman

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Have you any really interesting travel photos?
We would love to publish them in our newsletter. Not only will you win fame and glory with your name published ... if the photo is published in our newsletter,
you will win a first aid kit valued at $35.


If you do have an interesting travel photo, (especially those with a health theme) send it to TMA care of info@travelmedicine.com.au.


Outbreak Information and News

Tick Borne Encephalitis (TBE) has been found on Zealand

Tick Borne Encephalitis (TBE) has been found on Zealand as opposed to New Zealand ... Zealand is the largest island in Denmark ... the capital of Denmark, Copenhagen, is partly located on the eastern shore of Zealand.Tick Borne Encephalitis causes fever, influenza-like symptoms, headache, myalgia, and arthralgia. Long-lasting or permanent brain damage has been observed in 10-20% of infected patients. There is no specific treatment. The forests in northern Zealand are visited by more than 2.3 million people annually. Following these 2 cases of TBE, all forest workers have been offered vaccination against TBEV. Travellers to Europe need to be mindful of avoiding tick bites. More information.

Northern Hemisphere Flu

The composition of the Northern hemisphere flu vaccine for their autumn season is the same as our current southern hemisphere seasonal flu vaccine. I think that is good reason for extra encouragement to our travelers to have flu vaccination before they travel. Dr Christine Aus, TMA Newcastle.

Germany - Hantavirus

According to state health authorities, 85 cases of hantavirus infection, a significant increase over the average incidence, have been confirmed in Baden-Wurttemberg's Stuggart District so far this year. Hantavirus is transmitted by rodents and, although risk to the typical traveler is minimal, contact with rodent droppings and rodent urine should be avoided.

Fiji - Cyclone Tomas

On March 14, Cyclone Tomas hit Fiji with heavy rainfall and very strong winds. Northern and eastern areas of Fiji have been declared emergency zones. Power, telecommunication systems, and local infrastructure have been affected. Travelers should monitor local weather forecasts and follow the advice of local authorities.

Turkey - Earthquake

On March 8, 2010, a 6.0-magnitude earthquake struck Elazig Province. Casualties and damage to infrastructure have been reported. Landslides and strong aftershocks are possible. Travelers should avoid affected areas and monitor local media reports.

Kenya, Rwanda, Uganda - Flooding

Heavy rains have caused flooding and mudslides throughout the country. Evacuations, casualties, and damage to infrastructure have been reported. Provision of essential services has been disrupted. Travelers should monitor local news and weather reports and follow the advice of local authorities.

Sri Lanka - Dengue

According to Sri Lanka's Ministry of Health, approximately 8,600 suspected cases of dengue fever, a significant increase over the average incidence, have been reported so far this year, primarily from the districts of Jaffna, Gampaha, and Colombo. Travelers are advised to practice daytime insect precautions.

Honduras - Dengue

According to the Honduran Ministry of Health, approximately 2,500 suspected cases of dengue fever, a significant increase over the average incidence, have been reported so far this year. Areas most affected include the metropolitan areas of Central District and Atlantida, Olancho, and Yoro Departments. Travelers are advised to practice daytime insect precautions.

Argentina - Dengue

According to the Argentine Ministry of Health, more than 500 cases of dengue fever, a significant increase over the average incidence, have been reported from Misiones Province so far this year. Travelers are advised to practice daytime insect precautions.

...Prepared by Dr Campbell Crilly, Cairns, Travel Medical Alliance


Lhasa to Kathmandu via mountain bike

In September October 2009 I undertook a cycling challenge in aid of the Oncology Children's Foundation with the aim of raising funds for gene therapy research and we succeeded above all expectations in raising over $90,000. The three Toowoomba riders from a group of fourteen raised over half the amount.

We flew into Lhasa and had a few days acclimatising and getting supplies and bikes in order. The trip covered the Frienship Highway with a side trip to Everest Base Camp and Rongbok Monastery. We passed several peaks over 5000 metres with some super descents. My descending skills were a little hesitant at first as last April I had a minor bingle involving fractured collar bone and four ribs. Luckily I recovered well and was able to get the necessary training hours in to undertake the trip.

We camped and used some "guest houses" over the journey and after a week the tents were the preferred option even if it was minus seven in the mornings. Some towns we stayed in had the noisiest dogs on the planet. The group bonded very well together, it never ceases to amaze me how Aussies all stick together through the most trying conditions. Our leader from Raw travel did an absolutely superb job on keeping morale high as everyone had an off day here or there. Altitude issues were quite minimal due to our initial four days in Lhasa as cycling over 5000 metres is not for the faint hearted but everybody succeeded at their own tempo. The scenery on the Himalayan Plateau while stark is equally stunning and we were rewarded with some amazing vistas at the various peaks we crossed. Having been in Bhutan the year before it was interesting looking South over the range and realising we were generally a 1000 metres higher.

The Tibetan people were naturally very inquisitive about us and we had lots of school kids high five us along the way. The most arduous part was when we left the highway for Base Camp. Riding through someone's rock garden springs to mind. One of our group, a fit 35 year old tri-athlete had cerebral oedema at Base Camp oxygen sats 72%, but responded well to dexamethasone and we descended next day anyway.

Once we reached Nyalem we were on the last leg and the next day we descended 4000 metres over 60 kilometres to the Nepalese border and the crossing itself was a surreal experience between the two countries.

We had a few days rest at The Last Resort just inside the Nepalese border where the house red was Jacob's Creek! Overall the cycling was almost the easy part as the camping and low temperatures were a bit of a shock even coming from Toowoomba.

To use the old cliche "it was a life changing experience" and feel very privileged to have gotten so close to Everest at 5300 metres but have no desires to climb it.

...Prepared by Dr Cormac Carey, Toowoomba, Travel Medical Alliance


Close To Home - Lessons From A Dengue Epidemic In North Queensland

In late 2008 and early 2009 North Queensland experienced its worst epidemic of dengue fever infections for 50 years. In total 1025 people were confirmed to be infected with one fatality recorded of an infected individual. Dengue fever is not naturally occurring in North Queensland and the cause of the outbreak was from infected international travellers with local transmission occurring thereafter. Dengue fever viral infection has been increasing globally since the 1970's and it is estimated that between 50 and 100million people are infected annually with 250,000 people affected by Dengue haemorrhagic fever. Dengue fever is the most common mosquito borne viral disease affecting humans globally.

Dengue Fever

Dengue is a virus belonging to the flaviviridaea family of viruses that includes Yellow fever, Japanese encephalitis, Nile valley fever and Chikagunya fever. Infection with one of four serotypes of dengue confers lifetime immunity to that serotype but no protection against the other serotypes. Clinically significant infection occurs in an urban - endemic cycle between humans and mosquitoes only.

Transmission occurs via the female Aedes aegypti mosquito biting an unsuspecting human. The Aedes mosquito is a lazy mosquito and enjoys the comforts of human habitation. It is a daytime biting mosquito and prefers to rest indoors feeding early morning or mid to late afternoon but may feed all day. The mosquito is a prolific breeder in discarded tyres, pot plants, blocked gutters and drains and other water bearing receptacles.

Dengue occurs worldwide in all tropical and subtropical areas but is increased during hot, humid and wet seasonal weather where conditions favour breeding. Dengue transmission is more intense in urban areas and the risk of infection is highest in South East Asia and South America. Transmission rates of one in 1000 travellers have been suggested but are dependant on many factors. Any traveller is at risk when visiting an endemic urban area. The risk of Dengue haemorrhagic fever is one hundred times greater for individuals who have been previously infected with a different serotype. Travellers who have a history of infection need specific advice in regard to the risk of DHF.

Clinically symptoms of dengue fever occur 2-7 days after infection and notable for the abrupt onset of fever with headache, retro-orbital pain, backache, myalgia, arthralgia, weakness, nausea and vomiting. Approximately 50% of individuals will develop a rash initially on the trunk but it may spread to the extremities and the face. The initial infection is usually self-limiting and the illness resolves after one week. Fatalities are not associated with a typical primary infection.

Dengue haemorrhagic fever occurs when an individual who has been previously infected by the dengue virus is re-infected with a different dengue serotype. The clinical presentation is the same but severe thrombocytopaenia develops with easy bruising, petechiae, effusions and hypo-proteinaemia. Severe shock may develop with specific organ impairment i.e. kidneys and DIC in rare cases.

The diagnosis of Dengue fever should be suspected in all travellers returning from endemic regions with a fever. Clinical symptoms are not dissimilar to many viral mosquito borne disease and if suspected early enough a Dengue RT- PCR blood test will detect the presence of the virus. Specific Dengue IgM and IgG should also be performed and repeated if necessary along with a full blood count, electrolytes, renal and liver function tests.

Treatment is symptomatic and supportive. Early detection of more severe disease symptoms requires hospitalisation. Advice on avoiding the spread of the disease to uninfected individuals where Aedes aegypti mosquitoes are present is crucial to avoiding a local epidemic.

Prevention of Dengue fever in travellers is about education on insect protective measures and the occurrence and spread of the disease. Specific travel advice is required to take into consideration the regions travelled and the mode of accommodation used. Public health measures in infected countries do help reduce the incidence of the disease but are hampered by cost, population apathy and weak enforcement of public health measures. A tetravalent Dengue vaccine is in development stage but is mooted to be many years away from clinical use.

The University of Queensland is conducting research into Wolbachia pipientis an intra-cellular bacterium that occurs naturally in many insects including mosquitoes. The bacteria is of interest in the control of dengue fever because a particular strain of the Wolbachia bacteria shortens the lifespan of the mosquito and appears to interfere with the mosquitoes capacity to transmit the disease. However the transmission of the infection does not readily occur between mosquitoes and is spread vertically from the female parent to the offspring. The Wolbachia research continues and if successful will have implications for other insect borne diseases such as malaria.


Bibliography: 1. Harrison's Principles of Internal Medicine 17th Edition (2008) Part 7- Infectious diseases, Section 15- Infections Due to RNA Viruses; Chapter 189 Infections Caused by Arthropod and Rodent borne Viruses-Clarence J. Peters introduction; 2. Queensland Government Tropical Public Health Unit Media releases 2008-2010 Updated 9th March 2010 3. Travax Medical Library 2010 4. www.eliminatedengue.org 5. www.who.int Dr. W.J.H.McBride; "Deaths associated with dengue haemorrhagic fever: the first in Australia in over a century" eMJA; 183(1): 35-37

...Prepared by Dr Campbell Crilly, Cairns, Travel Medical Alliance


Interesting travel photo - fish catches the fisherman

This is a photo of Ben a patient of mine who travelled to Peru for his honeymoon last year. He and his wife where on a river cruise approximately 150km east of Iquitos in the Amazon Tributaries when they noticed a large number of fish jumping around the boat. One of the fish struck him in the throat catching a spike in his neck. He also drove a spike into his thumb attempting to retrieve the fish. Neither the patient or the fish was harmed in the photo!

...Prepared by Dr Campbell Crilly, Cairns, Travel Medical Alliance

Have you any really interesting travel photos?
We would love to publish them in our newsletter. Not only will you win fame and glory with your name published ... if the photo is published in our newsletter,
you will win a first aid kit valued at $35.


If you do have an interesting travel photo, (especially those with a health theme) send it to TMA care of info@travelmedicine.com.au.


1300 42 11 42

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www.travelmedicine.com.au

Travel Medicine Alliance

The Travel Medicine Alliance
GPO Box 2832, Brisbane, Queensland, 4001, Australia

Ph: 07 3221 9066
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Email: info@travelmedicine.com.au
www.travelmedicine.com.au

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